Neonatal Endocrinology and Diabetes

Neonatal Endocrinology is a medical subspecialty dealing with disorders of the endocrine glands, such as growth disorders, sexual differentiation in neonates, diabetes and other disorders. The other type of diabetes that is often misdiagnosed as type 1 or type 2 diabetes, called  monogenic diabetes which is seen in newborn babies. Endocrine disorders in neonates are caused by too many or too few hormones circulating throughout the body. If a newborn baby has problem with growth, diabetes, hormone-producing glands that help maintain growth and development, puberty, energy level and mood. Neonatal/ Pediatric endocrinologists are usually the primary physicians involved in the medical care of infants with intersex disorders.

Neonatal diabetes mellitus (NDM) is defined as a disease that affects an infant and their body's ability to produce or use insulin. It is a monogenic (controlled by a single gene) form of diabetes that occurs in the first 6 months of life. Infants with NDM do not produce enough insulin, leading to an increase in blood glucose. Maturity onset diabetes of the young (MODY) MODY is a rare form of diabetes which is different from both Type 1 and Type 2 diabetes, and runs strongly in families. MODY is caused by a mutation (or change) in a single gene. NDM is a rare condition accounting for up to 1 in 400,000 infants in the United States. Permanent neonatal diabetes mellitus is a type of diabetes that first appears within the first 6 months of life and persists throughout the lifespan.

 

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